Herper - The Herper package is a simple toolset to install and manage conda packages and environments from R

Many tools for data analysis are not available in R, but are present in public repositories like conda. The Herper package provides a comprehensive set of functions to interact with the conda package managament system. With Herper users can install, manage and run conda packages from the comfort of their R session. Herper also provides an ad-hoc approach to handling external system requirements for R packages. For people developing packages with python conda dependencies we recommend using basilisk (https://bioconductor.org/packages/release/bioc/html/basilisk.html) to internally support these system requirments pre-hoc.

Last updated 24 days ago

infrastructuresoftware

6.28 score 5 stars 51 scripts 250 downloads

soGGi - Visualise ChIP-seq, MNase-seq and motif occurrence as aggregate plots Summarised Over Grouped Genomic Intervals

The soGGi package provides a toolset to create genomic interval aggregate/summary plots of signal or motif occurence from BAM and bigWig files as well as PWM, rlelist, GRanges and GAlignments Bioconductor objects. soGGi allows for normalisation, transformation and arithmetic operation on and between summary plot objects as well as grouping and subsetting of plots by GRanges objects and user supplied metadata. Plots are created using the GGplot2 libary to allow user defined manipulation of the returned plot object. Coupled together, soGGi features a broad set of methods to visualise genomics data in the context of groups of genomic intervals such as genes, superenhancers and transcription factor binding events.

Last updated 24 days ago

sequencingchipseqcoverage

4.49 score 1 packages 51 scripts 497 downloads

ChIPQC - Quality metrics for ChIPseq data

Quality metrics for ChIPseq data.

Last updated 24 days ago

sequencingchipseqqualitycontrolreportwriting

4.44 score 137 scripts 634 downloads

basecallQC - Working with Illumina Basecalling and Demultiplexing input and output files

The basecallQC package provides tools to work with Illumina bcl2Fastq (versions >= 2.1.7) software.Prior to basecalling and demultiplexing using the bcl2Fastq software, basecallQC functions allow the user to update Illumina sample sheets from versions <= 1.8.9 to >= 2.1.7 standards, clean sample sheets of common problems such as invalid sample names and IDs, create read and index basemasks and the bcl2Fastq command. Following the generation of basecalled and demultiplexed data, the basecallQC packages allows the user to generate HTML tables, plots and a self contained report of summary metrics from Illumina XML output files.

Last updated 24 days ago

sequencinginfrastructuredataimportqualitycontrol

4.32 score 21 scripts 214 downloads

profileplyr - Visualization and annotation of read signal over genomic ranges with profileplyr

Quick and straightforward visualization of read signal over genomic intervals is key for generating hypotheses from sequencing data sets (e.g. ChIP-seq, ATAC-seq, bisulfite/methyl-seq). Many tools both inside and outside of R and Bioconductor are available to explore these types of data, and they typically start with a bigWig or BAM file and end with some representation of the signal (e.g. heatmap). profileplyr leverages many Bioconductor tools to allow for both flexibility and additional functionality in workflows that end with visualization of the read signal.

Last updated 24 days ago

chipseqdataimportsequencingchiponchipcoverage

3.99 score 49 scripts 406 downloads

tracktables - Build IGV tracks and HTML reports

Methods to create complex IGV genome browser sessions and dynamic IGV reports in HTML pages.

Last updated 24 days ago

sequencingreportwriting

3.87 score 37 scripts 278 downloads

Rfastp - An Ultra-Fast and All-in-One Fastq Preprocessor (Quality Control, Adapter, low quality and polyX trimming) and UMI Sequence Parsing).

Rfastp is an R wrapper of fastp developed in c++. fastp performs quality control for fastq files. including low quality bases trimming, polyX trimming, adapter auto-detection and trimming, paired-end reads merging, UMI sequence/id handling. Rfastp can concatenate multiple files into one file (like shell command cat) and accept multiple files as input.

Last updated 24 days ago

qualitycontrolsequencingpreprocessingsoftware

3.78 score 30 scripts 298 downloads